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Structural analysis of mtEXO mitochondrial RNA degradosome reveals tight coupling of nuclease and he

By 2020-11-11 No Comments

Nature Communications2018, vol 9, 1, pp. 97

DOI:10.1038/s41467-017-02570-5

Abstract

The mitochondrial RNA degradosome (mtEXO) plays an essential role in the regulation of mitochondrial gene expression and is composed of the 3′-to-5′ exoribonuclease Dss1 and the helicase Suv3. Here the authors present the RNA bound mtEXO crystal structure and give insights into its mechanism.

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